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프라그마틱 정품 사이트 are studies designed to inform the practice of clinical trials in real life. They are often focused on practical aspects of the study design, including the recruitment and consent process, adherence, and the use of commonly available equipment.
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A practical trial that employs a variety investigators and includes participants from diverse geographical locations is the Home Blood Pressure Management study (HBPM). This type of heterogeneity, which is vital for pragmatic trials to be valid and lessen the chance of bias is also essential. However excessive heterogeneity could lead to problems with the design of the trial.
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The goal of pragmatic trials is to replicate real-life scenarios and gain the highest level of validity externally. They are typically ordered by policymakers and practitioners in order to inform their decisions. They also provide a useful method of determining the causality between an intervention and its results. However, they shouldn't be used to substitute for explanation studies.
The pragmatism idea is controversial, and there are questions about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which validate the clinical or physiological hypothesis and pragmatic trials that inform the practice and policy decisions. They also proposed a framework called PRECIS for pragmatic trials.2 The tool was designed to define the elements of a pragmatic research study that includes recruitment, design, implementation of the intervention and follow-up.
The number of pragmatic trials is increasing. A recent Medline search using the terms naturalistic and pragmatic, limited to randomized controlled trials (RCTs), yielded 34 articles, as shown in red in Figure 2. This is an indication that the health sciences community is becoming more acquaint to the subject of pragmatic thinking. However, it is important to remember that the majority of these studies were conducted in primary care settings.